Patient samples will be obtained from skin that is to be discarded from patients presenting for reconstructive or aesthetic procedures necessitating skin excision. No other procedures or follow-up is needed for research purposes.

Inclusion/Exclusion Criteria

Inclusion

Age 18-35 or 50 and over

English Speaking

Able to provide consent

Undergoing reconstructive or aesthetic procedures necessitating skin excision at the scalp or abdomen

Exclusion

Known collagen disorder

Strong personal history of keloid formation

Deemed unfit for general anesthesia

Active infection of skin where samples may be taken