Genome-wide pooled CRISPR screening in neurospheres

Tanaz Abid, Amy B. Goodale, Zohra Kalani, Meghan Wyatt, Elizabeth M. Gonzalez, Kevin Ning Zhou, Kenin Qian, Dana Novikov, Alexandra-Larisa Condurat, Pratiti Bandopadhayay, Federica Piccioni, Nicole S. Persky, David E. Root

Published: 2023-06-06 DOI: 10.1038/s41596-023-00835-6

CRISPR screening

neurospheres

spheroid cultures

genome-wide

cell line screening

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Spheroid culture systems have allowed in vitro propagation of cells unable to grow in canonical cell culturing conditions, and may capture cellular contexts that model tumor growth better than current model systems. The insights gleaned from genome-wide c
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ACKNOWLEDGMENTS

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Genome-wide pooled CRISPR screening in neurospheres

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