Hyperspectral confocal imaging for high-throughput readout and analysis of bio-integrated microlasers
Vera M. Titze, Soraya Caixeiro, Vinh San Dinh, Matthias König, Matthias Rübsam, Nachiket Pathak, Anna-Lena Schumacher, Maximilian Germer, Christian Kukat, Carien M. Niessen, Marcel Schubert, Malte C. Gather
Published: 2024-01-18 DOI: 10.1038/s41596-023-00924-6
bio-integrated microlasers
hyperspectral confocal imaging
high-throughput readout
intracellular biosensing
multiplexed cell tracking
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Supplementary information
Supplementary Information
Supplementary Notes 1–3, Figs. 1–15 and Tables 1–3
Reporting Summary
Supplementary Video
Dynamic refractive index sensing of glucose diffusion. x-y maximum intensity projection (MIP) (left) and x-z MIP (center) of the hyperspectral confocal z-stack, color-coded by fitted refractive index, with exemplary raw lasing spectra and calculated external refractive index changes (right). All panels are synchronized.
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