Patient-derived and mouse endo-ectocervical organoid generation, genetic manipulation and applications to model infection

Rajendra Kumar Gurumurthy, Stefanie Koster, Naveen Kumar, Thomas F. Meyer, Cindrilla Chumduri

Published: 2022-05-10 DOI: 10.1038/s41596-022-00695-6

Organoids

Cervical Cancer

Genetic Manipulation

Infection Modeling

Stem Cells

AI 解读

Efficient and safe single-cell cloning of human pluripotent stem cells using the CEPT cocktail

Profiling native pulmonary basement membrane stiffness using atomic force microscopy

Genetic circuit design automation with Cello 2.0

Synthesis of siRNA nanoparticles to silence plaque-destabilizing gene in atherosclerotic lesional macrophages

Scalable dual-omics profiling with single-nucleus chromatin accessibility and mRNA expression sequencing 2 (SNARE-seq2)

A practical guide to scanning light-field microscopy with digital adaptive optics

Effective high-throughput isolation of fully human antibodies targeting infectious pathogens

Improved sampling and DNA extraction procedures for microbiome analysis in food-processing environments

MOF-derived nanoporous carbons with diverse tunable nanoarchitectures

Tutorial: a statistical genetics guide to identifying HLA alleles driving complex disease

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The cervix is the gateway to the upper female reproductive tract, connecting the uterus and vagina. It plays crucial roles in fertility and pregnancy maintenance from onset until delivery of the fetus, and prevents pathogen ascension. Compromised function
Introduction
Materials
Reagents
Equipment
Reagent setup
Procedures
Troubleshooting
Timing
Anticipated results
- References
References
ACKNOWLEDGMENTS
ACKNOWLEDGMENTS

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Patient-derived and mouse endo-ectocervical organoid generation, genetic manipulation and applications to model infection

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