Preparing ductal epithelial organoids for high-spatial-resolution molecular profiling using mass spectrometry imaging

Brenda Bakker, Rianne D. W. Vaes, Merel R. Aberle, Tessa Welbers, Thomas Hankemeier, Sander S. Rensen, Steven W. M. Olde Damink, Ron M. A. Heeren

Published: 2022-02-17 DOI: 10.1038/s41596-021-00661-8

organoids

mass spectrometry imaging

3D morphological structure

gelatin embedding

molecular profiling

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Organoid culture systems are self-renewing, three-dimensional (3D) models derived from pluripotent stem cells, adult derived stem cells or cancer cells that recapitulate key molecular and structural characteristics of their tissue of origin. They generall
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References
ACKNOWLEDGMENTS
ACKNOWLEDGMENTS

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Preparing ductal epithelial organoids for high-spatial-resolution molecular profiling using mass spectrometry imaging

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