Engineering SARS-CoV-2 using a reverse genetic system

Xuping Xie, Kumari G. Lokugamage, Xianwen Zhang, Michelle N. Vu, Antonio E. Muruato, Vineet D. Menachery, Pei-Yong Shi

Published: 2021-01-28 DOI: 10.1038/s41596-021-00491-8

SARS-CoV-2

reverse genetics

virus engineering

cDNA clone

COVID-19 research

AI 解读

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Reverse genetic systems are a critical tool for studying viruses and identifying countermeasures. In response to the ongoing COVID-19 pandemic, we recently developed an infectious complementary DNA (cDNA) clone for severe acute respiratory syndrome corona
Introduction
Materials
Procedure
Troubleshooting
Timing
Anticipated results
- Reporting Summary
- References
References
ACKNOWLEDGMENTS

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Engineering SARS-CoV-2 using a reverse genetic system

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Supplementary Information

Reporting Summary

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