Recombinant extracellular vesicles as biological reference material for method development, data normalization and assessment of (pre-)analytical variables

Edward Geeurickx, Lien Lippens, Pekka Rappu, Bruno G. De Geest, Olivier De Wever, An Hendrix

Published: 2021-01-14 DOI: 10.1038/s41596-020-00446-5

recombinant extracellular vesicles

biological reference material

method development

data normalization

pre-analytical variables

AI 解读

Supplementary information

Supplementary Information

Supplementary Fig. 1.

Reporting Summary

Supplementary Data 1

Source data of Fig. 4.

Supplementary Data 2

Source data of Fig. 5.

Supplementary Data 3

Source data of Fig. 6.

Supplementary Data 4

Source data of Fig. 7.

Generation of mouse–human chimeric embryos

Genome-wide quantification of transcription factor binding at single-DNA-molecule resolution using methyl-transferase footprinting

Generation of CRISPR–Cas9-mediated genetic knockout human intestinal tissue–derived enteroid lines by lentivirus transduction and single-cell cloning

A puromycin-dependent activity-based sensing probe for histochemical staining of hydrogen peroxide in cells and animal tissues

Decoding personal biotic and abiotic airborne exposome

A clinically relevant model of focal embolic cerebral ischemia by thrombus and thrombolysis in rhesus monkeys

Bioengineering human intestinal mucosal grafts using patient-derived organoids, fibroblasts and scaffolds

Biomimetic tail-to-head terpene cyclizations using the resorcin[4]arene capsule catalyst

Neuroscience robotics for controlled induction and real-time assessment of hallucinations

Scanorama: integrating large and diverse single-cell transcriptomic datasets

Single-cell RNA sequencing (scRNA-seq)（单细胞RNA测序）

Data integration（数据集成）

Heterogeneity（异质性）

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References

Supplementary information

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